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polyclonal rabbit anti-mouse cxcl13 antibody (Thermo Fisher)

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Thermo Fisher polyclonal rabbit anti-mouse cxcl13 antibody
Polyclonal Rabbit Anti Mouse Cxcl13 Antibody, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/polyclonal rabbit anti-mouse cxcl13 antibody/product/Thermo Fisher
Average 90 stars, based on 1 article reviews

polyclonal rabbit anti-mouse cxcl13 antibody - by Bioz Stars, 2026-03

90/100 stars

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Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Primer sequences.

Article Snippet: The membrane was blocked with 5% skimmed milk for 1 h at room temperature, prior to an overnight incubation at 4°C with rabbit anti-mouse CXCL13 polyclonal antibody (dilution, 1:500; cat no. orb101825; Biorbyt Ltd., Cambridge, UK), rabbit anti-mouse CXCR5 monoclonal antibody (dilution, 1:500; cat no. orb5925; Biorbyt Ltd.), rabbit anti-p-ERK polyclonal antibody (dilution, 1:500; cat no. orb1733; Biorbyt Ltd.), rabbit anti-ERK polyclonal antibody (dilution, 1:500; cat no. orb224458; Biorbyt Ltd.) and rabbit anti-β-actin polyclonal antibody (dilution, 1:500; cat no. orb 129534; Biorbyt Ltd.).

Techniques:

Effect of CXCL13 on tumor volume in Control, Model and Inhibitor group mice. Female BALB/c mice were randomly divided into three groups: Control; Model (inoculated with 1×105 4T1 cells); Inhibitor (inoculated with 4 mg/kg goat anti-mouse CXCL13 polyclonal antibody at day −2, −1 and 0, then injected with 1×105 4T1 cells). The tumor volume of the three groups was calculated on days 6, 12 and 18. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13.

Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Effect of CXCL13 on tumor volume in Control, Model and Inhibitor group mice. Female BALB/c mice were randomly divided into three groups: Control; Model (inoculated with 1×105 4T1 cells); Inhibitor (inoculated with 4 mg/kg goat anti-mouse CXCL13 polyclonal antibody at day −2, −1 and 0, then injected with 1×105 4T1 cells). The tumor volume of the three groups was calculated on days 6, 12 and 18. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13.

Techniques: Control, Injection

Effects of CXCL13 on tumor morphology from H&E staining in the Model and Inhibitor groups. After 9 weeks, all mice were sacrificed and the tumor tissues were sectioned and H&E stained for morphology observation. Images are of ×100 magnification. CXCL13, C-X-C motif chemokine ligand 13; H&E, hematoxylin and eosin staining.

Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Effects of CXCL13 on tumor morphology from H&E staining in the Model and Inhibitor groups. After 9 weeks, all mice were sacrificed and the tumor tissues were sectioned and H&E stained for morphology observation. Images are of ×100 magnification. CXCL13, C-X-C motif chemokine ligand 13; H&E, hematoxylin and eosin staining.

Techniques: Staining

Effects of CXCL13 on the mRNA expression of 3 key genes of the CXCR5/ERK pathway (CXCL13, CXCR5 and ERK) in the Control, Model and Inhibitor groups. The relative mRNA expression was normalized to β-actin. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13; CXCR5, C-X-C motif chemokine receptor 5; ERK, extracellular-regulated protein kinases; p-ERK, phosphorylated-ERK.

Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Effects of CXCL13 on the mRNA expression of 3 key genes of the CXCR5/ERK pathway (CXCL13, CXCR5 and ERK) in the Control, Model and Inhibitor groups. The relative mRNA expression was normalized to β-actin. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13; CXCR5, C-X-C motif chemokine receptor 5; ERK, extracellular-regulated protein kinases; p-ERK, phosphorylated-ERK.

Techniques: Expressing, Control

Effects of CXCL13 on the expression levels of three key proteins of the CXCR5/ERK pathway (CXCL13, CXCR5 and p-ERK) was analyzed in the Control, Model and Inhibitor groups. (A) Western blot analysis demonstrating that CXCL13, CXCR5 and p-ERK protein levels increased, with an increased p-ERK/ERK ratio, in the Model and Inhibitor groups compared with those in the Control group. The protein levels of CXCL13, CXCR5 and p-ERK decreased and the ratio of p-ERK/ERK decreased with CXCL13 inhibition. (B) Quantification of the western blot allowed for statistical analysis of the relative levels of proteins (normalized to β-actin). *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C Motif Chemokine Ligand 13; CXCR5, C-X-C motif chemokine receptor 5; ERK, extracellular-regulated protein kinases; p-ERK, phosphorylated-ERK.

Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Effects of CXCL13 on the expression levels of three key proteins of the CXCR5/ERK pathway (CXCL13, CXCR5 and p-ERK) was analyzed in the Control, Model and Inhibitor groups. (A) Western blot analysis demonstrating that CXCL13, CXCR5 and p-ERK protein levels increased, with an increased p-ERK/ERK ratio, in the Model and Inhibitor groups compared with those in the Control group. The protein levels of CXCL13, CXCR5 and p-ERK decreased and the ratio of p-ERK/ERK decreased with CXCL13 inhibition. (B) Quantification of the western blot allowed for statistical analysis of the relative levels of proteins (normalized to β-actin). *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C Motif Chemokine Ligand 13; CXCR5, C-X-C motif chemokine receptor 5; ERK, extracellular-regulated protein kinases; p-ERK, phosphorylated-ERK.

Techniques: Expressing, Control, Western Blot, Inhibition

Effects of CXCL13 on the concentrations of three cytokines (IL-1β, TNF and TGF-β1) were analyzed by ELISA in the Control, Model and Inhibitor groups. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13; IL-1β, interleukin-1β; TNF, tumor necrosis factor; TGF-β1, transforming growth factor β1.

Journal: Oncology Letters

Article Title: Signaling via the CXCR5/ERK pathway is mediated by CXCL13 in mice with breast cancer

doi: 10.3892/ol.2018.8510

Figure Lengend Snippet: Effects of CXCL13 on the concentrations of three cytokines (IL-1β, TNF and TGF-β1) were analyzed by ELISA in the Control, Model and Inhibitor groups. *P<0.05 vs. Control group; #P<0.05 vs. Model group. CXCL13, C-X-C motif chemokine ligand 13; IL-1β, interleukin-1β; TNF, tumor necrosis factor; TGF-β1, transforming growth factor β1.

Techniques: Enzyme-linked Immunosorbent Assay, Control

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